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Adrien Brody (Predators, King Kong 2005) and Sarah Polley star in the horror movie SPLICE, a Frankenstein-type tale of technology gone wrong.

Watch a film clip from SPLICE above. The human/animal clone turns against her maker.

Clive and Elsa are a pair of brilliant scientists whose cutting-edge experiments in genetic engineering make them superstars in their field. As devoted to their careers as they are to one another, they start conducting unauthorized experiments with new animal species that show great promise. Drunk with their god-like powers, they introduce human DNA into one of their creations, producing a creature that is greater than the sum of its parts: a rapidly developing animal/human hybrid that may be a step up on the evolutionary ladder.

While this female creature inspires maternal feelings in Elsa, she evokes something far-from-paternal in Clive, something that poses a threat to them all. Then, when this seemingly perfect organism makes a final, shocking metamorphosis, it is mankind itself that is threatened.

Warner Bros. Pictures

Release: 06/04/2010

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